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A PROCESS FOR THE PREPARATION OF ATOSIBAN ACETATE

机译:乙酸乙酸酯的制备方法

摘要

The present invention related to a process for the preparation of atosiban acetate using a novel non-linear liquid phase peptide synthesis scheme. This invention makes use of combing precursor peptides synthesised separately in high purity and yield over presently known processes. The disclosed process has several advances over known process like ease of scale-up and work-up as the process utilises liquid phase peptide preparation chemistry.
机译:本发明涉及使用新颖的非线性液相肽合成方案制备乙酸阿托西班的方法。本发明利用在目前已知的方法中以高纯度和高产率分别合成的精梳前体肽。由于该方法利用液相肽制备化学,因此所公开的方法与已知方法相比具有一些进步,例如易于规模化和后处理。

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