SULFOXIMINE SUBSTITUTED PYRIMIDINES AS CDK-AND /OR VEGF INHIBITORS THEIR PRODUCTION AND USE AS PHARMACEUTICAL AGENTS

摘要

This invention relates to pyrimidine derivatives of general formula I in which Q, R1, R2, R3, R4, R5, X and m have the meanings that are contained in the description, as inhibitors of cyclin-dependent kinases and VEGF-receptor tyrosine kinases, their production as well as their use as medications for treatment of various diseases.