Pharmaceutical compositions with increased activity comprising a sodium channel blocker and a selective serotonin reuptake inhibitor

摘要

Disclosed is a pharmaceutical composition which comprises a sodium channel blocker selected from the group consisting of lamotrigine, crobenetine, oxcarbamazepine and phosphenytoin and a selective serotonin reuptake inhibitor selected from the group consisting of fluoxetine, paroxetine, dulcxetine, sertraline, escitalopram and citalopram. Also disclosed is the use of a sodium channel blocker and a selective serotonin reuptake inhibitor as defined above in a process for the preparation of a pharmaceutical composition suitable for the treatment and/or the prevention of diseases in mammals, which involve chronic pain or epilepsy, or symptoms or diseases deriving from disorders and/or injuries of the motor system.