Dynamics of soluble cyclomethylguaranella

摘要

It refers to a different formula ring (I), where Z1 is ch or N; a is a formula ring (a),(b)Wherein, R4 is halide, asphalt (C1-C6),Among other things, D1 is ch, Cr4 or N, R7 is h, cycloquilo (C3-C6),Phenyl, etc.; L1 is O, s, CF2, etc.; L2 is (CH2) 2-4, CF2 or other; arilo (C6-C10),1.5 to 10 members of heterologous or cycloformyl (c3-c8);R5 is a tar (C1-C6),Alquenilo（C2-C6），Bicycle (C5-C8),R8 is an asphalt (C1-C4), among other things,O-Alquenilo（C2-C4），2 R11 is, inter Alia, h or tar (C1-C6). The most popular compounds are: acid 1 - [6 - [2 - [4 - (2-phenyl) benzene] oxygen] - phenyl pyridine-2-il] - 5 - (trifluoromethyl) - 1h-pyrazol-4-carboxilio, acido 1 - [6 - (2 - [4 - (4-chlorophenyl) benzene] oxygen} phenyl-2-il] - 5 - (trifluoromethyl) - 1h-pirazol-4-carboxilio, Acid 1 - [6 - (2 - [4 - (oxocyclohexal) bencil] oxi} phinil) piridin-2-il] - 5 - (trifluoroectane sulfonic acid) - 1h-pirazol-4-carboxillic, etc. He also mentioned a composer of pharmacology These compounds activate soluble mucocyclinase for the treatment of hypertension, thoracic blood vessels, heart failure, thrombosis