PROCESS FOR THE PREPARATION OF N-VINYL FUNCTIONAL DERIVATIVES OF 5,6-MEMBERED NITROGEN-CONTAINING HETEROCYCLES

摘要

The invention relates to organic chemistry, in particular to processes for the preparation of N-vinyl functional derivatives of 5,6-membered nitrogen-containing heterocycles. The process consists in interaction of nucleophilic reagents with heterocyclic systems, wherein compound of formula II interacts with Br, thereafter prepared compound III is subjected to nucleophilic cleavage using nucleophilic reagents such as NaOH, NaCO, HNAlk(HO) with the preparation of compound of formula I. The process is simple, doesnt require use of sophisticated instrumentation and not easily accessible reagents; the process in a unique manner works both in electron-deficient heterocyclic systems and in electron-donating systems, so it can be used as common one for functionalization of heterocyclic systems of any nature.