USE OF A REPLICATION-DEFICIENT POCKET VIRUS VECTOR TO INCREASE THE CD4 + T-CELL IMMUNE RESPONSE AGAINST ANTIGEN

摘要

There is provided a method of inducing a CD4+ T-cell response against a target antigen, by administering a composition a source of one or more CD4+ epitopes is a non-replicating or replication impaired recombinant poxvirus vector.