PREVENTIVE CANCER VACCINES BASED ON THE BORIS (BROTHER OF REGULATOR OF IMPRINTED SITES) MOLECULES

摘要

Polynucleotides encoding a nonfunctional mutant form of the Brother of Regulator of Imprinted Sites (BORIS) molecule, nonfunctional mutated BORIS protein, polypeptide or peptide and modified protein forms of BORIS are described. These molecules are used as a therapeutic vaccine against cancer.