medical device for modulation of neuronal activity in the brain.

摘要

Device for the desynchronization, controlled by the need, of a population of pathologic active neurons and rhythmically a patient, comprising: - a control unit (4), - a stimulator (1) for generating visual stimuli and / or auditory and / or tactile, having the form of pulses and are received by the patient, and - at least one means for detecting activities of the brain (2) of the patient, wherein the stimulator (1) and at least one means for detecting activities of the brain (2) are connected with the control unit (4), characterized in that - the control unit (4) comprises - a first means, which activates the stimulator (1) such that the stimulator (1) generates a pulse sequence, so that the frequency is varied, with the pulses of the pulse sequence are generated, and wherein the first means calculates, with the help of brain activity recorded means for detecting the activi ties of the brain (2) during the generation of the pulse sequence with which the first frequency of the pulses generated neural activity of the patient is excited, and - a second means, which activates the stimulator (1) such that the stimulator (1) generates a periodic pulse sequence, the pulses are generated with the first frequency, and a following pulse, wherein generating the periodic train of pulses and the next pulse is performed several times and in this case vary the time interval between the periodic train of pulses and the next pulse and intensity of the next pulse, wherein the second means calculates, with the help of brain activity recorded by the means for detecting activities of the brain ( 2) during multiple generation of the periodic train of pulses and the next pulse, how first time interval between the periodic train of pulses and pulse sig uiente and how first intensity of the next pulse the population of pathological active neurons dessincroniza and rhythmically more strongly, and - the control unit (4) is configured such that the control unit (4) after calculation the first frequency, the first time interval and the first intensity activates the stimulator (1) such that the stimulator (1) generates a periodic pulse sequence, the pulses are repeated with the first frequency, and a following pulse wherein the next pulse follows the first time interval to the periodic sequence of pulses and the next pulse has the first intensity.