Genetic construct, comprising: (i) a nucleotide sequence that forms a transcriptional enhancer of the production or expression of cytochrome P450 CYP3A4, and (ii) a gene encoding a reporter molecule, in which the nucleotide sequence includes each one of the following nuclear response elements of the 5 '' region - flanking CYP3A4: SEQ ID No. 2, SEQ ID No. 3, SEQ ID No. 4 and SEQ ID No. 5.
展开▼
机译:遗传构建体,其包含:(i)形成细胞色素P450 CYP3A4的产生或表达的转录增强子的核苷酸序列,和(ii)编码报告分子的基因,其中该核苷酸序列包括以下核反应中的每一个5''区域的元件-CYP3A4侧翼:SEQ ID No.2,SEQ ID No.3,SEQ ID No.4和SEQ ID No.5。
展开▼