Interdigitated sensor device based on antibodies marked with conductive nanoparticles and a procedure for the detection and quantification of substances present in liquids. (Machine-translation by Google Translate, not legally binding)

摘要

Interdigitated sensor device based on antibodies marked with conductive nanoparticles and a procedure for the detection and quantification of substances present in liquids. It comprises a matrix of interdigitated electrodes (4.1.1) coated with antigen to react with antibodies marked with conductive nanoparticles that are added after some substances to be detected and quantified, to the sensor, with one part of antibodies captured by the electrodes and another part it is captured by the molecules to be detected and quantified by reacting competitively with respect to the antigen, with said labeled antibodies, including means for detecting the variation in the electrical properties of the electrode matrix, caused by the labeled antibodies captured by said antigen layer. The method comprises making a first measurement of the electrical properties of the electrodes interdigitated with antigen, applying a solution of labeled antibodies and a substance to be detected, carrying out a second measurement and comparing the measurements. (Machine-translation by Google Translate, not legally binding)