PH RESPONSIVE BIODEGRADABLE POLYLACTIC ACID DERIVATIVES FORMING POLYMERIC MICELLES AND USES THEREOF FOR POORLY WATER SOLUBLE DRUG DELIVERY

摘要

Polylactic acid derivatives capable of forming micelles in an aqueous solutionwith a pH of 4 or above, having one terminal carboxyl group. The polylacticacid derivatives may be applied as a drug delivery system in various formssince poorly water soluble drugs can be entrapped inside the micelles.