Glycoprotein VI - FC fusion protein for treating vascular disorders

摘要

The invention provides use of an antibody against platelet glycoprotein VI (GPVI) for the preparation of a medicament for the prevention of intraarterial thrombosis in a patient characterized by (i) having suffered from an acute coronary or carotid syndrome and (ii)having active intraarterial lesions. Further, in vivo and in vivo screening methods for inhibitors or GP VI are provided and inhibitors identified thereby.