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1-sulfonyl-piperidine-3-carboxylic acid amide derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase for the treatment of type II diabetes mellitus

机译:1-磺酰基-哌啶-3-羧酸酰胺衍生物作为11-β-羟基类固醇脱氢酶的抑制剂,用于治疗II型糖尿病

摘要

Provided herein are compounds of the formula (1): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome.
机译:本文提供了式(1)的化合物:及其药学上可接受的盐,其中取代基如说明书中所公开的那些。这些化合物以及包含它们的药物组合物可用于治疗疾病,例如II型糖尿病和代谢综合症。

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