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Screening method for the identification of compositions suitable for the treatment of oral cavity malodor associated with smoking a tobacco product

机译:鉴定适于治疗与吸烟烟草制品有关的口腔恶臭的组合物的筛选方法

摘要

This invention generally relates to a screening method for identifying compositions suitable for use in an oral composition (e.g., a confection or chewing gum product) effective for the treatment of oral cavity malodor associated with smoking a tobacco product. In particular, this invention relates to a screening method for determining the ability of a composition to reduce the concentration of a pyridine or pyrazine compound present in a model sample or solution which is representative of the oral cavity of a subject after smoking a tobacco product, as an indicator of the effectiveness of that composition in the treatment of oral malodor associated with smoking a tobacco product.
机译:本发明一般涉及一种筛选方法,该方法用于鉴定适用于有效治疗与吸烟烟草制品有关的口腔恶臭的口腔用组合物(例如糖食或口香糖产品)的组合物。特别地,本发明涉及一种确定组合物降低代表吸烟者的模型样品或溶液中存在的吡啶或吡嗪化合物浓度的能力的模型,所述样品或溶液代表受试者吸烟后的口腔,作为该组合物在治疗与吸烟烟草制品有关的口腔恶臭中的有效性的指标。

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