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Treatment of heart failure in non-human animal mammals by an aldosterone antagonist

机译:醛固酮拮抗剂治疗非人类哺乳动物的心力衰竭

摘要

Veterinary composition for the treatment of heart deficiency in non-human mammalian subjects, comprises aldosterone antagonist, and vehicles, where the aldosterone antagonist is present in an effective therapeutic dose of greater than 1 mg/kg/day to less than 5 mg/kg/day, preferably 4 mg/kg/day, as a single dose. An independent claim is included for a veterinary kit for the treatment of heart failure in non-human subjects, comprising at least a compartment comprising a daily dose of the aldosterone antagonist of greater than 1 mg/kg/day to less than 5 mg/kg/day, preferably 4 mg/kg/day. ACTIVITY : Cardiant. MECHANISM OF ACTION : Aldosterone antagonist; Angiotensin converting enzyme inhibitors; Angiotensin II receptor AT-1 antagonists; Beta blocker; Calcium antagonists.
机译:用于治疗非人类哺乳动物受试者的心脏缺乏症的兽医用组合物,包括醛固酮拮抗剂和媒介物,其中醛固酮拮抗剂以大于1 mg / kg /天至小于5 mg / kg /天的有效治疗剂量存在单剂量,优选每天4mg / kg /天。包括用于治疗非人类受试者心力衰竭的兽医试剂盒的独立权利要求,其包括至少一个隔室,该隔室包含每日剂量大于1 mg / kg /天至小于5 mg / kg的醛固酮拮抗剂。 /天,优选4mg / kg /天。活动:Cardiant。作用机理:醛固酮拮抗剂;血管紧张素转换酶抑制剂;血管紧张素II受体AT-1拮抗剂; Β受体阻断药;钙拮抗剂。

著录项

  • 公开/公告号AU2008267227A8

    专利类型

  • 公开/公告日2010-02-18

    原文格式PDF

  • 申请/专利权人 CEVA SANTE ANIMALE;

    申请/专利号AU20080267227

  • 申请日2008-06-25

  • 分类号A61K31/585;A61K31/401;A61K31/50;A61K31/501;A61K31/55;A61K45/06;A61P9/04;

  • 国家 AU

  • 入库时间 2022-08-21 18:41:44

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