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Novel diphenyl 1,2,3-triazole derivatives useful as modulators of nicotinic acetylcholine receptors
Novel diphenyl 1,2,3-triazole derivatives useful as modulators of nicotinic acetylcholine receptors
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机译:新型二苯基1,2,3-三唑衍生物可用作烟碱型乙酰胆碱受体的调节剂
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摘要
This invention relates to novel diphenyl 1,2,3-triazole derivatives, which are found to be modulators of the nicotinic acetylcholine receptors. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
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