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TRANSPORT, DISTRIBUTION AND/OR EFFECTIVE SYSTEM IN ASEPTIC ADMINISTRATION

机译:无菌管理中的运输,分配和/或有效系统

摘要

The invention relates to an at least partially bioresorbable transport, distribution and/or effective system having a layer or sandwich structure, comprising a nonwoven material as a frame, into which collagen is built for configuring the layer and/or onto which collagen is bonded for configuring the sandwich structure. At least one of the surfaces of the transport, distribution and/or effective system comprises a substantially porous surface. Additionally, a pharmaceutical can be present. Furthermore, the system may comprise at least one osteoinductive or chondroinductive active substance, such as one of the differentiation and/or growth factors of the TGF ß-super family. The nonwoven material comprises fibers that are selected from cellulose fibers, such as rayon, polyester, polyacryl nitrile, optionally in combination with a super absorber. The invention further relates to a method for the production of the system and to the system as aseptic administration. To this end, the system is located in a container that is closed off by means of a plastic film molded part in the shape of a membrane-like film as a sterile barrier.
机译:具有层或夹心结构的至少部分可生物吸收的运输,分配和/或有效系统技术领域本发明涉及一种具有层或夹心结构的至少部分可生物吸收的运输,分配和/或有效系统,该结构包括无纺材料作为框架,在其中构造胶原蛋白以构成该层和/或在其上结合胶原蛋白以用于构造配置三明治结构。运输,分配和/或有效系统的至少一个表面包括基本上多孔的表面。另外,可以存在药物。此外,该系统可以包含至少一种骨诱导或软骨诱导活性物质,例如TGFβ-super家族的分化和​​/或生长因子之一。非织造材料包括选自纤维素纤维的纤维,例如人造纤维,聚酯,聚丙烯腈,任选地与超级吸收剂组合。本发明进一步涉及一种用于生产该系统的方法以及该系统作为无菌施用。为此,该系统位于容器中,该容器通过呈膜状薄膜形状的塑料薄膜成型部件作为无菌屏障封闭。

著录项

  • 公开/公告号WO2009083263A3

    专利类型

  • 公开/公告日2010-05-27

    原文格式PDF

  • 申请/专利权人 OSSACUR AG;BRIEST ARNE;

    申请/专利号WO2008EP11155

  • 发明设计人 BRIEST ARNE;

    申请日2008-12-31

  • 分类号A61L27/24;A61L27/54;A61L27/56;A61L27/58;

  • 国家 WO

  • 入库时间 2022-08-21 18:41:19

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