首页> 外国专利> SUSPENSION CONTAINING HYDRONIUM STABILIZED COLLOIDAL SILICIC ACID NANOPARTICLES, FORMULATION OBTAINED FROM THE SAID DILUTED SUSPENSION, POWDER OBTAINED FROM THE SAID DEHYDRATED SUSPENSION, COMPOSITIONS OBTAINED FROM THE SAID POWDER, PREPARATION AND U

SUSPENSION CONTAINING HYDRONIUM STABILIZED COLLOIDAL SILICIC ACID NANOPARTICLES, FORMULATION OBTAINED FROM THE SAID DILUTED SUSPENSION, POWDER OBTAINED FROM THE SAID DEHYDRATED SUSPENSION, COMPOSITIONS OBTAINED FROM THE SAID POWDER, PREPARATION AND U

机译:悬浮液中含有氢稳定的胶体硅酸纳米颗粒,该悬浮液由上述稀释的悬浮液制成,该粉末由上述的脱水悬浮液制成,该粉末由上述粉末,制备物和配制品组成

摘要

The present invention relates to hydronium stabilized silicic acid nanoparticles, to the formulation obtained from the said diluted suspension, to the powder obtained from the said dehydrated suspension and to the preparation or dosage form obtained from the said suspension, formulation or powder, to their preparation and their use in all kinds of applications in the domains of food, medicine, pharmaceutics, cosmetics. The present invention provides a stable suspension of colloidal silicic acid nanoparticles having a pH lower than 0.9, a molar silicon concentration between 0.035 and 0.65, a free water concentration of at least 30% (w/v) and a ratio between hydronium ion and Si molar concentrations higher than 2 and preferably inferior to 4. The present invention further provides a method for preparing a stable suspension of colloidal silicic acid nanoparticles, which comprises the steps of providing an aqueous inorganic or organic silicon solution and quick mixing said aqueous inorganic or organic silicon solution with water containing a strong acidic compound at a temperature inferior at 300°C, preferably comprised between 1 and 25°C, to form a suspension of colloidal silicic acid nanoparticles having a pH lower than 0.9, stabilized by hydronium ions, the ratio between hydronium ions and Si molar concentrations being higher than 2 and preferably inferior to 4, for a molar silicon concentration between 0.035 and 0.65 and a free water concentration of at least 30% (w/v).
机译:本发明涉及水合氢稳定的硅酸纳米颗粒,由所述稀释的悬浮液获得的制剂,由所述脱水的悬浮液获得的粉末,以及由所述悬浮液,制剂或粉末获得的制剂或剂型,及其制备方法及其在食品,医药,制药,化妆品领域的各种应用中的使用。本发明提供了pH低于0.9,硅的摩尔浓度为0.035至0.65,游离水浓度为至少30%(w / v)以及水合氢离子与Si之比的胶态硅酸纳米颗粒的稳定悬浮液。摩尔浓度高于2,优选低于4。本发明进一步提供了制备胶态硅酸纳米颗粒稳定悬浮液的方法,该方法包括以下步骤:提供无机或有机硅水溶液,并将所述无机或有机水溶液快速混合。硅溶液与含有强酸性化合物的水一起在低于300°C的温度下(最好介于1至25°C之间)形成pH值低于0.9的胶态硅酸纳米颗粒悬浮液,并通过水合氢离子稳定化,硅离子的摩尔浓度之间,水合氢离子与Si摩尔浓度之间的比值应大于2,最好小于4 en 0.035和0.65,游离水浓度至少为30%(w / v)。

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