首页> 外国专利> COMPOUNDS COMPRISING A 3-PYRIDINOL OR 5-PYRIMIDINOL RING HAVING AN ORGANOSELENO OR ORGANOTELLURO SUBSTITUENT FOR USE AS ANTIOXIDANTS

COMPOUNDS COMPRISING A 3-PYRIDINOL OR 5-PYRIMIDINOL RING HAVING AN ORGANOSELENO OR ORGANOTELLURO SUBSTITUENT FOR USE AS ANTIOXIDANTS

机译:包含3-吡咯烷酮或5-吡咯烷酮环的化合物,其具有有机硒酸或有机壬酸取代基用作抗氧化剂

摘要

Compounds comprising a 3-pyridinol or 5-pyrimidinol ring carrying an organoseleno- or organotelluro- substituent on the pyridine or pyrimidine ring, exhibit useful antioxidant properties. The compounds may for example be in accordance with the following formula (I) as defined herein. Catalytic chain-breaking and hydroperoxide decomposing antioxidant properties are also disclosed. Furthermore the compounds may be used in combination with a reducing agent. The compounds are useful for the stabilization of man-made and natural materials, or for the prevention or treatment of disorders caused by or involving free radical-mediated or oxidative tissue damage.
机译:包含在吡啶或嘧啶环上带有有机硒代或有机碲取代基的3-吡啶醇或5-嘧啶环的化合物表现出有用的抗氧化剂性能。所述化合物可以例如根据本文所定义的下式(I)。还公开了催化链断裂和氢过氧化物分解的抗氧化剂性质。此外,这些化合物可以与还原剂结合使用。该化合物可用于稳定人造和天然材料,或用于预防或治疗由自由基介导或氧化的组织损伤引起或涉及的疾病。

著录项

  • 公开/公告号WO2009144253A1

    专利类型

  • 公开/公告日2009-12-03

    原文格式PDF

  • 申请/专利号WO2009EP56468

  • 发明设计人 ENGMAN LARS;

    申请日2009-05-27

  • 分类号A61K31/44;A61K31/505;C07D213/60;C09K15/32;A61P39/06;

  • 国家 WO

  • 入库时间 2022-08-21 18:40:57

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