METHOD FOR PREDICITING THE CLINICAL OUTCOME OF PATIENTS WITH NON-SMALL-CELL LUNG CANCER TREATED WITH AN ANTI-METABOLITE PLUS AN ANTI-MICROTUBULE AGENT

摘要

The invention relates to an in vitro method for predicting the clinical outcome of patients suffering from non-small-cell lung cancer who have been treated with an anti- metabolite plus an anti-microtubule agent, based on the expression of BRCA1 gene, RRM1 gene and/or RRM2 gene in a sample from said patient, as well as a method for designing an individual therapy for a subject suffering from NSCLC and a kit useful in the implementation of the methodology described herein.