A HUMAN HOMOLOGUE OF THE DB4/ASK1 PROTEIN, NUCLEIC ACIDS, AND METHODS RELATED TO THE SAME

摘要

The present invention provides a human polypeptide homolog of DBF4/ASK1 and polynucleotides which identify and encode DRF1. In addition, the invention provides expression vectors, host cells and methods for its production. The invention also provides methods for the identification of DRF1 or DRF1-containing complex agonists/antagonists, useful for the treatment of human diseases and conditions.