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ADMINISTRATION BY INFUSION FOR THE TREATMENT OF ISCHEMIC EFFECTS

机译:通过输注进行局部缺血治疗

摘要

The present invention relates to the induction of hypothermia in humans, male and female, at any age, by use of a pharmaceutical composition to be administered parenterally by infusion or injection, comprising at least one compound selected among (1) vanilloid receptor agonists, capsaicinoids or capsaicinoid-like agonists reaching and binding to vanilloid receptors, and (2) cannabinoids or cannabimimetic agonists reaching and binding to cannabinoid receptors, and (3) adenosine receptor agonists, and (4) neurotensin receptor agonists, and (5) thyroxine derivatives, and (6) cytochrome c inhibitors, and (7) oxygen tension reducers, thereby inducing hypothermia, thus benefiting patients suffering from illnesses characterized by tissue anoxia.
机译:本发明涉及通过使用输注或注射剂肠胃外给药的药物组合物在任何年龄的男性和女性中诱导低温,该药物组合物包含选自(1)类香草素受体激动剂,辣椒素中的至少一种化合物或与类香草素受体结合的辣椒素样激动剂,以及(2)并与大麻素受体结合的大麻素或大麻素激动剂,以及(3)腺苷受体激动剂,和(4)神经降压素受体激动剂,以及(5)甲状腺素衍生物(6)细胞色素c抑制剂,和(7)降低氧气张力,从而引起体温过低,从而使患有组织缺氧性疾病的患者受益。

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