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CATHEPSIN L PROTEOLYTICALLY PROCESSES HISTONE H3 DURING MOUSE EMBROYONIC STEM CELL DIFFERENTIATION
CATHEPSIN L PROTEOLYTICALLY PROCESSES HISTONE H3 DURING MOUSE EMBROYONIC STEM CELL DIFFERENTIATION
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机译：小鼠胚胎干细胞分化过程中组织蛋白酶L蛋白化处理的组蛋白H3
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摘要
Methods and agents useful for modulating histone proteolysis, stem cell differentiation, and gene transcription and for treating cancer are disclosed. Antibodies or antigen binding fragments that selectively bind to histone- 3 cleavage products and are useful for diagnosing cancer and monitoring a subject's response to cancer treatment are also disclosed.
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