首页> 外国专利> TERTIARY CARBINAMINES HAVING SUBSTITUTED HETEROCYCLES, WHICH ARE ACTIVE AS INHIBITORS OF BETA-SECRETASE, FOR THE TREATMENT OF ALZHEIMER'S DISEASE

TERTIARY CARBINAMINES HAVING SUBSTITUTED HETEROCYCLES, WHICH ARE ACTIVE AS INHIBITORS OF BETA-SECRETASE, FOR THE TREATMENT OF ALZHEIMER'S DISEASE

机译:具有取代杂环的叔碳胺类化合物,它们可作为β-分泌酶的抑制剂,用于治疗老年痴呆症

摘要

The present invention is directed to tertiary carbinamine compounds having substituted heterocycles, which are inhibitors of the beta-secretase enzyme, and are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.
机译:本发明涉及具有取代的杂环的叔卡宾胺化合物,它们是β-分泌酶的抑制剂,可用于治疗涉及β-分泌酶的疾病,例如阿尔茨海默氏病。本发明还涉及包含这些化合物的药物组合物,以及这些化合物和组合物在治疗涉及β-分泌酶的疾病中的用途。

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