TERTIARY CARBINAMINES HAVING SUBSTITUTED HETEROCYCLES, WHICH ARE ACTIVE AS INHIBITORS OF BETA-SECRETASE, FOR THE TREATMENT OF ALZHEIMER'S DISEASE

摘要

The present invention is directed to tertiary carbinamine compounds having substituted heterocycles, which are inhibitors of the beta-secretase enzyme, and are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.