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The use of moxonidine salts for purification of moxonidine

机译:莫索尼定盐在纯化莫索尼定中的用途

摘要

The present invention provides crystalline Moxonidine salts e.g., mono-Moxonidine oxalate and mono-Moxonidine formate. Also provided by the present invention is a novel purification process of Moxonidine using these crystalline Moxonidine salts. By precipitating a Moxonidine salt from the reaction mixture and reacting it with a base, highly pure crystalline Moxonidine base is obtained in high yield.
机译:本发明提供结晶的莫索尼定盐,例如草酸单莫索尼定和甲酸单莫索尼定。本发明还提供了使用这些结晶的莫索尼定盐的新颖的莫索尼定纯化方法。通过从反应混合物中沉淀莫索尼定盐并使之与碱反应,可以高收率获得高纯度的结晶莫索尼定碱。

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