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CONSTRUCTION OF RECOMBINANT ADENOVIRUS WITH GENES THAT CODIFY FOR SAG1, SAG2 AND SAG3

机译:编码SAG1,SAG2和SAG3的基因重组腺病毒的构建

摘要

This invention refers to the construction of recombinant adenovirus with genes that codify for T. gondii SAG1, SAG2 and SAG3, through a homologue recombination technique between two vectors. A first vector that serves as transference vector of genes and a second vector that bears the adenoviral receptor genome of these genes. The invention is also related to the use of recombinant adenovirus in a vaccine composition to obtain the immunization against infections caused by T. gondii parasite.
机译:本发明涉及通过两个载体之间的同源重组技术,构建具有编码弓形虫SAG1,SAG2和SAG3的基因的重组腺病毒。用作基因的转移载体的第一载体和带有这些基因的腺病毒受体基因组的第二载体。本发明还涉及重组腺病毒在疫苗组合物中用于获得针对弓形虫寄生虫引起的感染的免疫的用途。

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