首页> 外国专利> PHARMACOLOGICALLY ACCEPTABLE SALT OF 1,3,4OXADIAZOLE COMPOUND OR HYDRATE THEREOF

PHARMACOLOGICALLY ACCEPTABLE SALT OF 1,3,4OXADIAZOLE COMPOUND OR HYDRATE THEREOF

机译:[1,3,4]恶二唑化合物或其水合物的药理学可接受的盐

摘要

A pharmacologically acceptable salt of a compound (1), which has an FXa inhibitory effect and is useful as a pharmaceutical compound for prevention/treatment of thrombotic and/or embolic diseases, a hydrate thereof, a crystal of the salt or hydrate, and methods for commercially producing the same. Specifically disclosed is a pharmacologically acceptable salt of N1-(5-chloropyridin-2-yl)-N2-[(1S,2R,4S)-2-{[(5-methyl- 4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino}-4-([1,3,4]oxadiazol-2-yl)cyclohexyl]ethanediamide, a hydrate thereof, or a crystal of the salt or hydrate.
机译:具有FXa抑制作用并可用作预防/治疗血栓和/或栓塞性疾病的药物化合物的化合物(1)的可药用盐,其水合物,盐或水合物的晶体和方法用于商业生产。具体公开的是N1-(5-氯吡啶-2-基)-N2-[(1S,2R,4S)-2-{[(5-甲基-4,5,6,7-四氢噻唑[ 5,4-c]吡啶-2--2-基)羰基]氨基} -4-([1,3,4]恶二唑-2-基)环己基]乙二酰胺,其水合物或盐或水合物的晶体。

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