CYTOMETRIC METHOD FOR THE COMPARATIVE ANALYSIS OF THE LENGTH OF PCR PRODUCTS AND USES OF THIS METHOD

摘要

The present invention relates to a method for the comparative analysis of the length of PCR products by cytometer. The invention also relates to the various uses of said method, especially detecting genetic alterations by cytometric analysis of the length of PCR products. Different DNA size changes or sequence alterations, i.e. triplet-expansions, insertions, deletions, microsatellite polymorphisms, or SNPs (single nucleotide polymorphisms), mutations can be detected with the method of the invention. Therefore, this method is suitable for diagnosing or screening the diseases and unique characteristics associated with these genetic traits and for screening the genetic traits which are important from agricultural points of view. The present invention also relates to the kits for carrying out the method described above.