TREATMENT OF INFLAMMATION AND THE COMPLEMENT AND KININ CASCADES IN A PATIENT, PARTICULARLY IN CHRONIC ULCEROUS SKIN LESIONS

摘要

The invention provides methods of inhibiting inflammation and/or the complement cascade and/or the kinin cascade in a human or non-human animal patient, particularly in a wound (for example, a chronic ulcerous skin lesion) in a human or non-human mammal (particularly a human). The affected location of the patient is contacted with a hydrogel composition comprising a hydrophilic polymer carrying multiple pendant sulphonyl groups, optionally with multiple pendant carboxylic groups, on each polymer molecule.