DIAGNOSTIC METHOD FOR NEPHROTIC SYNDROME, PROPHYLACTIC OR THERAPEUTIC AGENT FOR NEPHROTIC SYNDROME, AND METHOD FOR SCREENING THE PROPHYLACTIC OR THERAPEUTIC AGENT

摘要

A single nucleotide polymorphism of a nucleotide located on Glypican-5 gene or a single nucleotide polymorphism of a nucleotide that is in linkage disequilibrium with the aforementioned nucleotide is analyzed, and nephrotic syndrome is diagnosed based on the results of the analysis.  The screening for a prophylactic or therapeutic agent for nephrotic syndrome is achieved by selecting a substance that can alter the expression level of Glypican-5.  A pharmaceutical preparation for preventing or treating nephrotic syndrome is provided, which comprises a fibroblast growth factor (FGF) signaling inhibitor as an active ingredient.