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Biosynthesis of polyketide synthase substrates
Biosynthesis of polyketide synthase substrates
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机译:聚酮化合物合酶底物的生物合成
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摘要
The use of enzymes which catalyze the production of starter and extender units for polyketides is described. These enzymes may be used to enhance the yield ofpolyketides that are natively produced or polyketides that are rationally designed. By using these techniques, the synthesis of a complete polyketide has been achieved in E. coli. This achievement permits a host organism with desirable characteristics to be used in the production of such polyketides and to assess the results of gene shuffling.
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