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GENETIC VARIANTS USEFUL FOR RISK ASSESSMENT OF CORONARY ARTERY DISEASE AND MYOCARDIAL INFARCTION

机译:可用于评估冠状动脉疾病和心肌梗塞风险的遗传变异

摘要

The invention relates to methods of risk assessment and diagnosis of susceptibility to coronary artery disease and myocardial infarction, by assessing the presence or absence of alleles of certain polymorphic markers found to be associated with coronary artery disease and myocardial infarction. The invention also relates to methods for use of such polymorphic markers for predicting drug response to drugs for treating cardiovascular disease, or for monitoring the effectiveness of such drugs. The invention further relates to kits encompassing reagents for use in these methods.
机译:本发明涉及通过评估发现某些与冠心病和心肌梗塞有关的多态性标志物的等位基因的存在或不存在,来评估对冠心病和心肌梗塞的易感性的风险的方法。本发明还涉及使用这种多态性标记物预测对治疗心血管疾病的药物的药物反应或监测此类药物的有效性的方法。本发明进一步涉及包含用于这些方法的试剂的试剂盒。

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