PHARMACEUTICAL AGENT FOR PREVENTION OR TREATMENT OF RETARDED NERVE REGENERATION INDUCED BY DIABETES

摘要

Disclosed is a pharmaceutical agent for preventing or treating retarded nerve regeneration induced by diabetes.Specifically disclosed is a prophylactic or therapeutic agent for diabetic neuropathy, which comprises a compound represented by general formula (I) [wherein R1 represents a C1-C4 alkyl group; R2 and R3 independently represent a hydrogen atom or a C1-C4 alkyl group; R4 represents a hydrogen atom or a C1-C4 alkyl group; R5 represents a hydrogen atom, a C1-C4 alkyl group, a C2-C5 alkanoyloxymethyl or 1-(C2-C5 alkanoyloxy)ethyl group, a C1-C4 alkoxycarbonyloxymethyl or 1-(C1-C4 alkoxycarbonyloxy)ethyl group, a (5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl group, a (5-phenyl-2-oxo-1,3-dioxolen-4-yl)methyl group, or a phthalidyl group; and R6 represents a carboxy group or a tetrazol-5-yl group], or a pharmacologically acceptable salt or a pharmacologically acceptable ester thereof as an active ingredient.