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H-FABP AS EARLY PREDICTOR OF MYOCARDIAL INFARCTION

机译:H-FABP作为心肌梗死的早期预测者

摘要

The present invention relates to a method for diagnosing myocardial infarction in a subject who suffers from acute coronary syndrome and has a cardiac Troponin level, which is detectable, but lower than the level that is considered as being indicative for a myocardial infarction. Moreover, the present invention relates to a method for identifying a subject being susceptible to cardiac intervention, wherein the subject suffers from acute coronary syndrome and has a cardiac Troponin level which is detectable, but lower than a level that is considered as being indicative for a myocardial infarction. The methods of the present invention are based on the determination of H-FABP and, optionally, myoglobin in a sample of said subject and comparing the amount of H-FABP and, optionally, myoglobin to reference amounts. Also comprised by the present invention are kits or devices to carry out the methods of the present invention.
机译:本发明涉及一种用于诊断患有急性冠状动脉综合征并具有心肌肌钙蛋白水平的受试者的心肌梗塞的方法,该水平是可检测的,但是低于被认为指示心肌梗塞的水平。此外,本发明涉及一种用于识别易受心脏干预的对象的方法,其中所述对象患有急性冠状动脉综合症并且具有可检测的心脏肌钙蛋白水平,但低于被认为指示心脏钙蛋白的水平。心肌梗塞。本发明的方法基于所述受试者的样品中H-FABP和任选的肌红蛋白的测定,并将H-FABP和任选的肌红蛋白的量与参考量进行比较。本发明还包括进行本发明方法的试剂盒或装置。

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