首页>
外国专利>
METHOD OF PREDICTING DRUG-INDUCED PHOSPHOLIPIDOSIS
METHOD OF PREDICTING DRUG-INDUCED PHOSPHOLIPIDOSIS
展开▼
机译:药物诱导的磷脂质的预测方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention provides a method of predicting drug-induced phospholipidosis, comprising a step of contacting a mammalian cell with a test compound, a step of measuring extracellular and/or intracellular lysosomal enzyme level or activity, or measuring intracellular LC3 level, and a step of selecting a test compound that has enhanced extracellular secretion of the enzyme or increased the protein level as a compound capable of inducing drug-induced phospholipidosis.
展开▼