首页> 外国专利> USE OF NF-KAPPAB INHIBITOR SN50 AND OPTIONALLY ANGIOTENSIN III AS THERAPEUTIC AGENTS IN THE TREATMENT OF EG HBV INFECTION

USE OF NF-KAPPAB INHIBITOR SN50 AND OPTIONALLY ANGIOTENSIN III AS THERAPEUTIC AGENTS IN THE TREATMENT OF EG HBV INFECTION

机译:NF-KAPPAB抑制剂SN50和可选血管紧张素III在治疗EG HBV感染中的治疗作用

摘要

The present invention is directed to the use of the peptide compound Pro-Ala-Leu-Pro-Glu-Asp-Gly-Gly-Ser-Gly-Ala-Phe-Pro-Pro-Gly-His-Phe-Lys-Asp-Pro-Lys-Arg-Leu-Tyr as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Pro-Ala-Leu-Pro-Glu-Asp-Gly-Gly-Ser-Gly-Ala-Phe-Pro-Pro-Gly-His-Phe-Lys-Asp-Pro-Lys-Arg-Leu-Tyr optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
机译:本发明涉及肽化合物Pro-Ala-Leu-Pro-Glu-Asp-Gly-Gly-Ser-Gly-Ala-Phe-Pro-Pro-Gly-His-Phe-Lys-Asp-的肽的用途Pro-Lys-Arg-Leu-Tyr作为预防和/或治疗癌症,自身免疫性疾病,纤维化疾病,炎性疾病,神经退行性疾病,传染病,肺病,心脏和血管疾病以及代谢性疾病的治疗剂。此外,本发明涉及药物组合物,其优选为冻干物或液体缓冲溶液或人工母乳制剂或母乳替代物形式,其包含肽Pro-Ala-Leu-Pro-Glu-Asp-Gly-Gly-Ser-Gly- Ala-Phe-Pro-Pro-Gly-His-Phe-Lys-Asp-Pro-Lys-Arg-Leu-Tyr任选地与至少一种药学上可接受的载体,冷冻保护剂,冻干保护剂,赋形剂和/或稀释剂一起。

著录项

  • 公开/公告号EP2197469A2

    专利类型

  • 公开/公告日2010-06-23

    原文格式PDF

  • 申请/专利权人 MONDOBIOTECH LABORATORIES AG;

    申请/专利号EP20080802060

  • 申请日2008-09-09

  • 分类号A61K38/17;A61K38/08;A61P31/20;A61P3;A61P9;A61P11;A61P25/28;A61P31;A61P35;A61P37;A61P31/18;A61P31/06;

  • 国家 EP

  • 入库时间 2022-08-21 18:34:57

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