INHIBITOR OF SCAR FORMATION AT INJURED TISSUE, WHICH CONTAINS GRANULOCYTE MACTOPHAGE-COLONY STIMULATING FACTOR(GM-CSF)

摘要

PURPOSE: An inhibitor of scar formation of injured tissue is provided to suppress expression of GFAP and/or CSPGs core protein and to regenerate injured nerve tissue.;CONSTITUTION: An inhibitor of scar formation of injured tissue contains granulocyte macrophage-colony stimulating factor(GM-CSF) as an active ingredient. The inhibitor is neuroglia lesion inhibitor. The injured tissue is central nervous system such as spinal cord or brain. The inhibitor contains the GM-CSF, carrier for delivering active ingredient, support or transmitter. The carrier is formed in a membrane, sponge, powder, or gel. The carrier is PGA(polyglycolic acid), PLGA(poly(lactic co-glycolic acid)), collagen, gellatin or fibrin.;COPYRIGHT KIPO 2010