CELL AGGREGATE-HYDROGEL-POLYMER SCAFFOLD COMPLEX FOR CARTILAGE REGENERATION, METHOD FOR THE PREPARATION THEREOF AND COMPOSITION COMPRISING THE SAME

摘要

The present invention provides the useful differentiated cell populations of the hydrogel to cartilage damage cartilage collective-polymer scaffold compound treatment, method for their preparation, it is related to the composition for treating cartilage damage as an active component, particularly, the hydrogel composites cell colony differentiation that the pore of the cartilage cell and polymer scaffold that are entered in hydrogel matrix by the aggregation of distribution differentiated cell population are inoculated in this polymer scaffold cell colony collective enters cartilage cell, and to useful treatment cartilage damage, that is injected-hydrogel-polymer scaffold the complex of collective, to the composition for treating cartilage damage as preparation method, it includes active component. Cell colony is distinguished according to the present invention enters cartilage cell, and hydrogel-polymer scaffold complex of collective can be excellent in terms of mechanical strength and flexibility when maintaining a constant shape and effectively causes the regeneration for the cartilage for being similar to natural cartilage to damage repair of cartilage to be used as a useful therapeutic agents and be.