CELL AGGREGATE-HYDROGEL-POLYMER SCAFFOLD COMPLEX FOR CARTILAGE REGENERATION, METHOD FOR THE PREPARATION THEREOF AND COMPOSITION COMPRISING THE SAME

摘要

The present invention provides a differentiated cell populations useful in the treatment of cartilage damage cartilage collective-hydrogel-polymer scaffold complexes, methods for their preparation, and it relates to a composition for the treatment of cartilage damaged as an active ingredient, specifically, by dispersing the aggregates of differentiated cell population into chondrocytes in the hydrogel matrix and the pores of the polymer scaffold was inoculated in this polymer scaffold cell population collective-hydrogel composite cell population is differentiated into cartilage cells useful in the treatment of cartilage damage that is injected collective-hydrogel-polymer scaffold complex, to a composition for the treatment of cartilage damaged as a preparation method thereof, and it containing the active ingredient. Cell population is differentiated into chondrocytes in accordance with the present invention, collective-hydrogel-polymer scaffold complex can be excellent in mechanical strength and flexibility while maintaining a constant shape and effectively induce the regeneration of the cartilage similar to natural cartilage to repair of cartilage injury may be used as a very useful therapeutic agents for.