TABLET OR CAPSULE CONTAINING COATING PELLET OF COMPOSITE HAVING ORLISTAT AND ATTAPULGITE WHICH PREVENTS OUTFLOW OF OIL FROM ANUS

摘要

PURPOSE: A coating pellet of composite containing orlistat and attapulgite is provided to prevent outflow of oil from anus and prevent and treat obesity.;CONSTITUTION: A pellet of composite containing orlistat and attapulgite contains: a pellet containing attapulgite; a first layer which is an enteric coating layer of the attapulgite-containing pellet; and a second layer containing orlistat which covers the first layer. The first layer contains Eudragit(methacrylic acid copolymer) as enteric coating layer. The second layer contains orlistat and hydroxypropylmethylcellulose. The pellet further contains an intermediate layer between the first layer and second layer. A method for preparing composite pellet of attapulgite and orlistat comprises: a method for preparing pellet containing the attapulgite; a step of forming enteric coating layer on the pellet; and a step of covering the first layer and forming orlistat-containing layer with the second layer.;COPYRIGHT KIPO 2010