首页> 外国专利> METHOD OF PRODUCING 3-O-ALKYL-5,6-O-1-METHYLETHYLIDENE-L-ASCORBIC ACID AND METHOD OF PRODUCING 5,6-O-1-METHYLETHYLIDENE-L-ASCORBIC ACID

METHOD OF PRODUCING 3-O-ALKYL-5,6-O-1-METHYLETHYLIDENE-L-ASCORBIC ACID AND METHOD OF PRODUCING 5,6-O-1-METHYLETHYLIDENE-L-ASCORBIC ACID

机译:生产3-O-烷基-5,6-O-1-甲基亚乙基-L-抗坏血酸的方法和生产5,6-O-1-甲基亚乙基-L-抗坏血酸的方法

摘要

The L- ascorbic acid and acetone by reacting a blank and under the acid catalyst generated in the first step, a first step of generating a -L- ascorbic acid (1-methyl-butylidene) 5,6-O- 5, (1-methyl-butylidene) 6-O- -L- ascorbic acid and by reacting the alkylating agent in the presence of a base 3-O- alkyl -5,6-O- (1-methyl-butylidene on) -L- a second step of generating ascorbic acid 3-O- alkyl -5,6-O- (1- methyl butylidene) -L- in the production method of the ascorbic acid, the first step is two electric , 2-dimethoxy-3-O- alkyl -5,6-O- -L- method of producing ascorbic acid (1-methyl-butylidene a) is characterized as done in the presence of propane. ; According to the present invention, since the separation and purification without the -L- ascorbate (in 1-methyl-butylidene) reaction of the intermediate, 5,6-O-, the first process and the second process can be performed in the same reaction liquid system Therefore, the reaction process is extremely simple. ; According to the present invention, as, industrial production methods by performing the first step and the second step in the same reaction liquid system, are also advantageously to also operate as a gyeongjesang. ; According to the present invention, the first step is 2,2-electricity that is conducted in the presence of dimethoxypropane, since the first step of the reaction to proceed quantitatively, 3-O- which can satisfy industrially alkyl -5 , (1-methyl-butylidene) 6-O- can be obtained a yield of -L- ascorbate. ; 3-O- alkyl -5,6-O- (1-methyl-butylidene) -L- ascorbate
机译:L-抗坏血酸与丙酮反应,使空白反应在第一步生成的酸催化剂下进行,第一步生成-L-抗坏血酸(1-甲基-丁烯)5,6-O-5,(1 -甲基-亚丁基)6 -O- -L-抗坏血酸,并通过在碱式3-O-烷基-5,6-O-(1-甲基-亚丁基)-L- a存在下使烷基化剂反应在抗坏血酸的生产方法中生成抗坏血酸3-O-烷基-5,6-O-(1-甲基丁烯)-L-的第二步,第一步是两个电,2-二甲氧基-3-O -烷基-5,6-O--L-生产抗坏血酸(1-甲基-亚丁基a)的方法的特征在于在丙烷存在下进行。 ;根据本发明,由于中间体5,6-O-不经-L-抗坏血酸酯(在1-甲基丁烯中)反应进行分离和纯化,因此第一步骤和第二步骤可以在同一步骤中进行。反应液体系因此,反应过程极为简单。 ;同样,根据本发明,通过在同一反应液系统中执行第一步和第二步的工业生产方法,也有利地还可以作为京釜使用。 ;根据本发明,第一步是在二甲氧基丙烷存在下进行的2,2-电,因为反应的第一步是定量地进行的3-O-,其可以工业上满足烷基-5,(1-可以得到-L-抗坏血酸酯的甲基-亚丁基)6-O-。 ; 3-O-烷基-5,6-O-(1-甲基丁烯)-L-抗坏血酸酯

著录项

  • 公开/公告号KR100974608B1

    专利类型

  • 公开/公告日2010-08-09

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20080030225

  • 发明设计人 구쓰마 데루오;

    申请日2008-04-01

  • 分类号C07D307/62;

  • 国家 KR

  • 入库时间 2022-08-21 18:30:58

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