METHOD FOR THE TREATMENT OF EXPERIMENTAL myocardial infarction in rats

摘要

1. A method of treatment of experimental myocardial infarction, based on modeling of myocardial infarction with subsequent medical intervention, characterized in that the intravenous administration is performed L-17 compound from the class of 1,3,4-thiadiazines dosage of 40 mg / kg after creation of myocardial infarction model, with followed by histological examination of myocardial tissue. ! 2. A method according to claim 1, characterized in that the compounds L-17, acting on the nature of the reaction ostrovospalitelnoy (reduces delivery of neutrophils that produce inflammation stimulating factors) corrects during the acute phase of systemic inflammatory response syndrome, which reduces the expression of leukocyte reaction, stimulates the migration of cells immunocompetent lymphocytes, plasma cells, mast cells, macrophages in the necrotic foci, accelerates the formation of granulation tissue with proliferation of fibroblasts cells nical number and causes substitution of necrotic area of ​​scar tissue provided active fibroblasts and fibrous structures.