COMPOSITION FOR ORAL USE CONTAINING NON-PATHOGENIC MICRO-ORGANISMS WITH THE ABILITY TO NORMALIZE THE INTESTINAL MICROFLORA (OPTIONS)

摘要

1. An oral composition containing non-pathogenic microorganisms and target additives, having the ability to normalize the intestinal microflora, characterized in that it is a powder comprising substances containing non-pathogenic microorganisms, dried in a culturing medium, selected from the following: bacteria of the genus Bifidobacterium and / or bacteria of the genus Lactobacillus, and / or species-specific virulent bacteriophages, and / or species-specific bacteriophages with induced virulence, or a combination thereof, wherein It contains targeted additives capable of forming a stable foam structure, selected from the range: polyethylene glycol, albumin, gelatin, pectin, casein, caseinate, casein hydrolyzate, hydroxypropyl cellulose, polyglucin, dextrin, tragacanth, aerosil, beckon, lactose or a mixture thereof, and is characterized by a porous structure fragility, with disintegration, has a relative shrinkage of at least 10%, equivalent pore diameter of 10-110 microns with a particle size of not more than 100 microns and a resting angle of less than 50 °, with the following ratio of components per 1.0 g of composition:! Bacteria of the genus Bifidobacterium 106-1010 CFU; and / or! Bacteria of the genus Lactobacillus 106-1010 CFU; and / or! Species-specific virulent bacteriophages with lytic activity not lower than 10-4 according to Appelman in relation to test strains and bacterial isolates isolated from the human body; and / or! Species-specific bacteriophages with induced virulence and / or with lytic activity not lower than 10-4 according to Appelman in relation to test strains and bacterial isolates isolated from the human body; targeted additives - the rest. ! 2. Oral composition containing non-pathogen