首页> 外国专利> THERAPEUTIC AND DIAGNOSTIC DRUG AND BIOLOGICALLY ACTIVE SUBSTANCE CARRIER AND APPLICATION THEREOF FOR MAKING DRUGS AND METHOD OF REGULATED CONTROLLED DRUG OR BIOLOGICALLY ACTIVE SUBSTANCE DELIVERY WITH REGULATED DESORPTION

THERAPEUTIC AND DIAGNOSTIC DRUG AND BIOLOGICALLY ACTIVE SUBSTANCE CARRIER AND APPLICATION THEREOF FOR MAKING DRUGS AND METHOD OF REGULATED CONTROLLED DRUG OR BIOLOGICALLY ACTIVE SUBSTANCE DELIVERY WITH REGULATED DESORPTION

机译:治疗性和诊断性药物及生物活性物质载体及其在制备药物中的应用以及通过调节脱附调节受控药物或生物活性物质的输送方法

摘要

FIELD: medicine.;SUBSTANCE: invention refers to a carrier for drugs, biologically active substances, biological objects used in medicine for diagnostics and treatment in pharmaceutical industry. The carrier represents a material sensitive to external magnetic or electric fields and consisting of magnetic or ferroelectric material filmed with biocompatible thermosensitive, biodegradable polymer and/or dispersed in thermosensitive medium properties of which change with varying temperature relative to that of human body within 15.9 to 42°C. The magnetic or ferroelectric materials are made of substance with great magnetocaloric or electrocaloric component effect 1 to 13 K, have temperature of magnetic or ferroelectric phase transition within temperature range 33 to 37°C, and are chosen from the group including rare-earth, transition and precious metals, their alloys and compounds.;EFFECT: invention also concerns methods of controlled drug delivery by means of such carrier with enabling release thereof (regulated desorption) in the preset point.;32 cl, 9 ex
机译:技术领域本发明是指用于药物,生物活性物质,用于医药工业中用于诊断和治疗的药物的生物物体的载体。载体代表一种对外部磁场或电场敏感的材料,由磁性或铁电材料制成,该材料被成膜为生物相容性热敏,可生物降解的聚合物和/或分散在热敏介质中,其性质相对于人体温度在15.9到42之间变化℃。磁性或铁电材料由磁热或电热成分效应为1到13 K的物质制成,磁或铁电相变温度在33到37°C的温度范围内,并且选自稀土,过渡金属效果:本发明还涉及通过这种载体控制药物递送的方法,该载体能够在预定点释放(调节的解吸)。32cl,9 ex

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