METHOD OF PREPARING THREE-COMPONENT COMPLEXES OF o-CRESOXYACETIC AND p-CHLORO-o-CRESOXYACETIC ACID WITH TRIETHANOLAMINE AND BIOGENEOUS METALS

摘要

FIELD: chemistry.;SUBSTANCE: method involves reacting triethanol ammonium salts of o-cresoxyacetic and p-chloro-o-cresoxyacetic acid with the corresponding metal salt in alcohol or aqueous medium preferably at room temperature for 1-48 hours. The three-component complexes are extracted through solvent distillation with subsequent washing of the formed powder with ether and drying in a vacuum. The said complexes can be used as a base for making medicinal drugs.;EFFECT: design of a method of preparing complexes of o-cresoxy- and p-chloro-o-cresoxyacetic acid, triethanolamine and metals having formula n[R(o-CH₃)-C₆H₃-OCH₂COO^-•N⁺H(CH₂CH₂OH)₃]•MX_m, where R = H, p-Cl; M = Mg, Ca, Mn, Co, Ni, Cu, Zn, Rh, Ag; X = CI, NO₃, CH₃COO; n = 1, 2; m = 1-3.;2 cl, 11 ex