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Preparing a solid drug with defined dose of an active substance, comprises preparing an active substance solution, adding determined amount of solution to a solid carrier in a vessel and removing the solvent present in the solution
Preparing a solid drug with defined dose of an active substance, comprises preparing an active substance solution, adding determined amount of solution to a solid carrier in a vessel and removing the solvent present in the solution
Preparing a solid drug, comprises (a) providing a solution by dissolving at least one active substance in at least one solvent, (b) providing a solid carrier and a vessel, (d) introducing the carrier material in vessel, (e) determining and adding the determined amount of the solution to solid carrier in the vessel, (g) removing the solvent, where the defined dose of the active substance remains on the carrier to obtain a solid drug containing the active ingredient and (h) repeating the steps for the application of other drugs on the solid carrier. Preparing a solid drug with a defined dose of at least one active substance, comprises: (a) providing a solution by dissolving at least one active substance in at least one solvent; (b) providing a solid carrier material; (c) providing a vessel; (d) introducing the carrier material into the vessel; (e) determining the amount of the solution from step (a), which corresponds to the defined dose of at least one active component; (f) adding the determined amount of solution to the solid carrier in the vessel; (g) removing the solvent, where the defined dose of the active substance or substances remain on the carrier to obtain a solid form of drug containing at least one active ingredient; (h) repeating the above steps for the application of other drugs on the solid carrier.
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机译: (54)标题:具有硅酸盐涂层的固体颗粒(54):FESTKoRPERPARTKEL MIT SILKATBESCHICHTUNG(57)摘要:本发明涉及一种具有二氧化硅涂层的固体颗粒的生产方法,其包括以下步骤:将固体颗粒分散为将其涂覆在水性介质中以产生固体颗粒分散体,通过缓冲系统调节固体颗粒分散体的pH以产生缓冲的固体颗粒分散体,并向缓冲的固体颗粒分散体中添加碱性硅酸盐溶液以形成二氧化硅在涂覆期间将其涂覆在固体颗粒上,其中选择缓冲体系和碱性硅酸盐溶液的量,使得在添加碱性硅酸盐溶液之前和在添加完成之后,缓冲的固体颗粒分散体的pH至少为7.0。碱性硅酸盐溶液的最大含量为11.0。固体颗粒优选是无机固体,特别是