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piperazinylalkylpyrazol derivatives for use as selective calcium channel blockers of the t type and methods for their manufacture
piperazinylalkylpyrazol derivatives for use as selective calcium channel blockers of the t type and methods for their manufacture
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机译:用作t型选择性钙通道阻滞剂的哌嗪基烷基吡唑衍生物及其制备方法
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摘要
The present invention provides for novel piperazinylalkylpyrazole derivatives, the preparation method thereof and the selective T-type calcium channel blocking activity thereof. Particularly, it provides a piperazinylalkylpyrazole derivative as represented by the formula set forth below or its pharmaceutically acceptable salts, and its preparation method thereof. The compound of Formula 1 is a novel piperazinylalkylpyrazole derivative, which particulary has T-type Ca 2+ channel blocking effect and thus can be useful as a therapeutic agent for nerve and muscle pain.
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