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multiple acting antiangiogene and cytotoxic compounds and methods for their use
multiple acting antiangiogene and cytotoxic compounds and methods for their use
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机译:多作用抗血管生成素和细胞毒性化合物及其使用方法
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摘要
This invention discloses pyrrolo pyrimidine compounds, and pharmaceutically acceptable salts, solvates and prodrugs thereof, of the following formula (3):These compounds are useful in therapeutically and/or prophylactically treating patients with cancer by inhibiting receptor tyrosine kinases and/or dihydrofolate reductase and/or thymidylate synthase. Methods of using these compounds, are also disclosed.
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