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Electrochemical sensor using a sugar with binding affinity for an analyte to be detected

机译:使用对待测分析物具有结合亲和力的糖的电化学传感器

摘要

The present invention provides an electrochemical sensor having a solid electrically conductive substrate and a compound immobilized thereon which has binding affinity for an analyte species to be detected and also displays electrochemical behaviour which is modified upon binding of that analyte species, so that binding of an analyte species can be detected by measuring electrochemical properties, such as by voltammetry. Desirably the immobilised compound contains both a first moiety with binding affinity for the analyte and a separate second moiety which is a redox system whose electrochemical oxidation/reduction properties become modified when the first moiety binds the analyte. The analyte binding moiety may be a diol or polyol and preferably is a sugar and further preferably deoxyribose. The electrochemical sensor finds use in methods of analysing reservoir and process fluids, particularly at a subterranean location to detect metals or boron presence. The electrochemical sensor may be a component of a downhole tool, adapted for deployment downhole.
机译:本发明提供了一种电化学传感器,其具有固体导电基底和固定在其上的化合物,该化合物对要检测的分析物具有结合亲和力,并且还显示出电化学行为,该电化学行为在结合该分析物时被修饰,从而使分析物结合可以通过测量电化学性质,例如通过伏安法来检测物种。理想地,固定化的化合物既包含对分析物具有结合亲和力的第一部分,又包含单独的第二部分,该第二部分是氧化还原系统,当第一部分结合分析物时其氧化/还原性质被修饰。分析物结合部分可以是二醇或多元醇,并且优选地是糖,并且进一步优选地是脱氧核糖。电化学传感器可用于分析储层和过程流体的方法中,尤其是在地下位置以检测金属或硼的存在。电化学传感器可以是适合于部署在井下的井下工具的部件。

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