首页> 外国专利> MICRORNA EFFECTIVE FOR DETECTING PRESENCE OF LIVER TUMOR LESION IN MAMMAL FOR SUPPLYING SPECIMEN

MICRORNA EFFECTIVE FOR DETECTING PRESENCE OF LIVER TUMOR LESION IN MAMMAL FOR SUPPLYING SPECIMEN

机译:微小RNA在检测供体标本哺乳动物中肝肿瘤病变中的作用

摘要

PPROBLEM TO BE SOLVED: To provide a cancer inspection method for accurately and simply evaluating the liver carcinogenesis of a chemical substance, and to provide a method for screening a mammal individual about the prime factor of liver cancer. PSOLUTION: There is provided a specific microRNA effective for detecting the presence of a liver tumor lesion in a mammal. The method for inspecting the liver tumor lesion in the mammal is characterized by comprising (1) the first process of measuring the content of one or more microRNAs selected from the group consisting of the following microRNAs, contained in a specimen supplied by the mammal, and (2) the second process of comparing the measurement value of the content of microRNA contained in the specimen, obtained in the first process, with the control value of the content of the microRNA, and then evaluating the presence or absence of the liver tumor lesion in the mammal for supplying the specimen on the basis of the difference. PCOPYRIGHT: (C)2011,JPO&INPIT
机译:<要解决的问题:提供一种癌症检查方法,以准确,简单地评估化学物质的肝脏致癌性,并提供一种筛选哺乳动物个体中肝癌主要因素的方法。

解决方案:提供了一种特定的微小RNA,可有效检测哺乳动物中肝肿瘤病变的存在。用于检查哺乳动物的肝肿瘤病变的方法的特征在于包括:(1)测量哺乳动物提供的标本中包含的一种或多种选自以下微RNA的微RNA的含量的第一过程,和(2)第二步,将在第一步中获得的标本中包含的微RNA含量的测量值与微RNA含量的对照值进行比较,然后评估肝肿瘤病变的存在与否。在哺乳动物中根据差异提供标本。

版权:(C)2011,日本特许厅&INPIT

著录项

  • 公开/公告号JP2011160677A

    专利类型

  • 公开/公告日2011-08-25

    原文格式PDF

  • 申请/专利权人 SUMITOMO CHEMICAL CO LTD;

    申请/专利号JP20100023981

  • 发明设计人 SUGATA TOKUO;SUMIDA KAYO;UWAKAWA MASARU;

    申请日2010-02-05

  • 分类号C12N15/09;C12Q1/68;C12M1;G01N33/53;G01N33/574;

  • 国家 JP

  • 入库时间 2022-08-21 18:25:17

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